Observation of central macular retinal microvascular network morphology of retinopathy of prematurity by optical coherence tomography angiography
10.13389/j.cnki.rao.2018.0083
- VernacularTitle:早产儿视网膜病变黄斑中心视网膜微血管形态特征:基于光学相干断层扫描血管成像(OCTA)的观察
- Author:
Yun-Xia LENG
1
;
Liu ZHANG
;
Meng ZHANG
;
Min WU
;
Cheng CAI
;
Guo-Liang REN
;
Zong-Yin GAO
Author Information
1. 510084 广东省广州市,广州市第一人民医院眼科,华南理工大学附属第二医院眼科
- Keywords:
retinopathy of prematurity;
optical coherence tomography angiography;
foveal avascular zone;
superficial retinal capillary plexus;
central foveal thickness
- From:
Recent Advances in Ophthalmology
2018;38(4):357-360
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the characteristics of central macular retinal microvascular network morphology of retinopathy of prematurity (ROP) with optical coherence tomography angiography(OCTA).Methods The 7-15 years old ROP children with laser treatment history(ROP group,25 eyes of 14 patients) and full-term children(control group,40 eyes of 20 patients) were collected by cross-sectional study.The subjects in the two groups were examined by RTVue XR Avanti-OCTA,and several parameters including the detection of the best corrected visual acuity (BCVA),central foveal thickness (CFT),foveal avascular zone (FAZ),macular superficial retinal capillary plexus (SCP) density were recorded and analyzed statistically with t test in the two groups.Results The area of FAZ in ROP group was (0.04 ± 0.05) mm2,which was significantly less than that in control group [(0.29 ± 0.08) mm2] (P ＜ 0.001).The SCP density of ROP group was 42.70％ ± 5.90％,which was significantly higher than that in the control group (35.90％ ± 6.30％) (P ＜ 0.001).The CFT in ROP group was (328.50 ± 34.90) μm,which was significantly higher than that in the control group [(236.80 ± 23.40)μm] (P ＜ 0.001).The BCVA was 0.83 ± 0.14 in ROP group and 0.85 ±0.26 in the control group,respectively,without significant difference (P ＞ 0.05).Conclusion ROP children have smaller or undefined FAZ,the thickened CFT and the increased SCP density,and the BCVA is not affected by the FAZ area and CFT in this study.
