Detective values of optical coherence tomography angiographyfor primary glaucoma
10.13389/j.cnki.rao.2018.0082
- VernacularTitle:光学相干断层扫描血管成像(OCTA)在原发性青光眼患者中的检测价值
- Author:
Yan ZHONG
1
;
Hui-Xin CHE
Author Information
1. 锦州医科大学
- Keywords:
optical coherence tomography angiography;
primary glaucoma;
vessel density;
retinal ganglion cells
- From:
Recent Advances in Ophthalmology
2018;38(4):352-356
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the diagnostic significance of optical coherence tomography angiography (OCTA) in the detection of primary glaucoma.Methods Totally 70 patients (116 eyes) of primary glaucoma were selected as the experimental group and 20 normal subjects (36 eyes) as the control group.The changes in macular vessel density,macular retinal ganglion cell (RGC) thickness,macular thickness,and optic disc retinal pigment epithelium (RPE) opening distance were measured by OCTA,and the correlation between the parameters and the mean deviation (MD) of visual field.Results When compared with the control group,the upper macular thickness,inferior macular thickness,macular RGC thickness and macular vessel density were reduced in the experimental group (all P ＜ 0.05).There was no significant difference in optic disc RPE opening distance between the control group and the experimental group (F =2.646,P =0.051 3).Linear positive correlations were found between macular thickness,macular RGC thickness,macular vessel density and MD (all r ＞ 0.5,P ＜0.01).The area under the curve of the diagnostic ROC curve of the macular vessel density,macular RGC thickness and mactlar thickness for glaucoma were all greater than 0.7.Conelusion There are linear positive correlations between macular thickness,macular RGC thickness,macular vessel density and MD.The parameters have a high diagnostic ability for the primary glaucoma.OCTA is a valuable technique for detecting glaucoma.
