Correlation between 320 row volume CT perfusion parameters of primary liver cancer and liver tumor volume and liver function Child-Pugh classification
10.7683/xxyxyxb.2018.01.016
- VernacularTitle:原发性肝癌320排容积CT灌注参数值与肿瘤体积及肝功能Child-Pugh分级的相关性
- Author:
Chang-Hua LIANG
1
;
Hua-Jie MAO
;
Pan LIANG
;
Yan-Long HU
;
Hui-Jie ZHANG
;
Dong-Dong WANG
;
Jian-Bo GAO
Author Information
1. 新乡医学院第一附属医院放射科
- Keywords:
primary liver cancer;
hepatic functional reserve;
Child-Pugh classification;
computed tomography;
CT perfusion imaging
- From:
Journal of Xinxiang Medical College
2018;35(1):65-68
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between the values of total tumor perfusion parameters in primary hepatocellular carcinoma and tumor volume and peritumoral perfusion parameters,and analyze its correlation with liver ChildPugh classification.Methods Forty-seven patients with primary liver cancer in the First Affiliated Hospital of Zhengzhou University from January 2013 to January 2015 were selected to perform 320 row volume CT perfusion imaging.The parameters of hepatic artery perfusion(HAP),portal vein perfusion(PVP) and hepatic perfusion index(HAPI) in tumor and peritumoral liver tissues were calculated based on total tumor measurement.The relationship between tumor perfusion parameters and ChildPugh classification of liver function,tumor volume and total tumor perfusion parameters,total tumor perfusion parameters and peritumoral perfusion parameters were analyzed.Results There was no correlation between tumor volume and total tumor perfusion parameters,peritumoral perfusion parameters (P ＞ 0.05),and there was no correlation between total tumor perfusion parameters and peritumoral perfusion parameters(P ＞0.05).There were significant differences between HAP,PVP and HAP of total tumor perfusion in different liver Child-Pugh classifications(P ＜ 0.05).With the increase of Child-Pugh classification of liver function,the HAP and HAPI of tumor gradually increased while PVP gradually decreased (P ＜ 0.05).Conclusions There is no correlation between tumor volume,total tumor perfusion parameters and peritumoral perfusion parameters.There is also no correlation between total tumor perfusion parameters and peritumoral perfusion parameters.There are significant differences in perfusion parameters between different Child-Pugh classifications of liver function,and the perfusion parameters obtained by the total tumor measurement can be used as the imaging indexes to reflect liver reserve function.
