Therapeutic effect of clopidogrel combined aspirin on acute myocardial infarction
10.3969/j.issn.1008-0074.2018.05.16
- VernacularTitle:氯吡格雷联合阿司匹林治疗急性心肌梗死的临床效果
- Author:
Zhao-Xia JIN
1
;
Li-Peng WAN
;
Yan-Qiong QIN
Author Information
1. 黄冈市中心医院心内科
- Keywords:
Myocardial infarction;
Aspirin;
Clopidogrel
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2018;27(5):554-557
- CountryChina
- Language:Chinese
-
Abstract:
Objective :To comprehensively analyze therapeutic effect of clopidogrel combined aspirin on acute myo-cardial infarction (AMI).Methods :A total of 100 AMI patients treated in our hospital were selected ,and equally divided into clopidogrel group and combined treatment group (received clopidogrel combined aspirin ).Both groups received routine treatment for 4 weeks .Total effective rate ,platelet aggregation rate (PAR) ,coronary recanaliza-tion time ,prothrombin time (PT) ,left ventricular ejection fraction (LVEF) and incidence rate of cardiovascular e-vents during hospitalization were compared between two groups .Results :Total effective rate of combined treatment group was significantly higher than that of clopidogrel group (96. 00% vs.80.00%, P＝0.014).Compared with clopidogrel group after treatment ,there were significant reductions in PAR [ (47.63 ± 7.83)% vs.(38.45 ± 8.55)%] ,incidence rate of cardiovascular events (24.00% vs.4.00%) and coronary recanalization time [(45.44 ± 4.42) vs.(41.93 ± 5.85)] ,P and significant rise in LVEF [ (48.56 ± 5.79)% vs.(55.51 ± 6.44)%] in combined treatment group , P＜0. 01 all.Conclusion : The clinical effect of clopidogrel combined with aspirin in the treatment of acute myocardial infarction is significant .
