Relationship among CRP ,MAP levels and no-reflow during emergency PCI in patients with acute myocardial infarction
10.3969/j.issn.1008-0074.2018.05.07
- VernacularTitle:急性心肌梗死患者CRP、MPV水平与急诊介入术中无复流的关系研究
- Author:
Kai-Jian HUANG
1
;
De-Qi LIN
;
Mao-Hai LIN
Author Information
1. 福建省莆田市第一医院心内科
- Keywords:
Myocardial infarction;
No-reflow phenomenon;
Angioplasty,balloon,coronary
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2018;27(5):520-523
- CountryChina
- Language:Chinese
-
Abstract:
Objective :To explore relationship among levels of C reactive protein (CRP) ,mean platelet volume (MPV) and occurrence of no-reflow (NR) during primary percutaneous coronary intervention (PCI) in patients with acute ST elevation myocardial infarction (STEMI).Methods :Clinical and imaging data of 156 STEMI patients ,who received primary PCI from Jan 2015 to Dec 2016 ,were retrospectively analyzed .According to presence of NR during PCI ,patients were divided into NR group (n=54) and no NR control group (n=102).Multi-factor Logistic regression analysis was used to analyze influencing factors of NR occurrence .Results :Compared with no NR control group ,there were significant rise in percent-age of diabetes mellitus (23.5% vs.42.6%) ,levels of CRP [(31.7 ± 5.3)mg/Lvs.(64.5 ± 9.7)mg/L]and MPV [(9.31 ± 1.05)fl vs.(11.29 ± 0.98)fl] ,number of stents [(1.9 ± 0.4) vs.(2.1 ± 0.6)] and symptom-onset-to-balloon [SOTB , (254 ± 96)min vs.(315 ± 108)min] in NR group , P<0.05 or <0.01. Multi-factor Logistic regression analysis indicated that diabetes mellitus ,SOTB ,levels of CRP and MPV were independent risk factors for NR occurrence (OR=2.335~3.670 ,P<0.05 or <0.01).Conclusion :Rise of CRP and MPV levels are independent risk factors for no-reflow during primary PCI in STEMI patients ,which possess certain predictive value for no-reflow occurrence and worth extending .