Correlation between diabetic peripheral neuropathy and cardiovascular diseases in patients with type 2 diabetes mellitus
10.3969/j.issn.1008-0074.2018.03.11
- VernacularTitle:2型糖尿病患者周围神经病变与心血管疾病的相关性
- Author:
Xiu-Rong XIE
1
;
Long-Zhen YAN
;
Xiao-Su BAI
Author Information
1. 深圳市龙华新区人民医院景龙社区健康服务中心
- Keywords:
Diabetes mellitus,type 2;
Diabetic neuropathies;
Cardiovascular diseases;
The correlation
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2018;27(3):279-281
- CountryChina
- Language:Chinese
-
Abstract:
Objective :To explore correlation between diabetic peripheral neuropathy (DPN) and cardiovascular disea-ses (CVD) in patients with type 2 diabetes mellitus (T2DM).Methods :A total of 375 T2DM patients ,who were treated in our community health service center from Jan 2014 to Jul 2016 ,were selected .Demographic characteris-tics ,systolic blood pressure (SBP) ,blood lipids ,blood glucose ,electromyogram and CVD were collected in all sub-jects using questionnaire .According to complicated CVD or not ,patients were divided into CVD group (n＝54) and non-CVD group (n＝321).Correlation among all indexes and CVD risk were analyzed .Multifactor Logistic regres-sion analysis was used to analyze independent risk factors for CVD risk .Results :Among the 375 T2DM patients ,54 cases (14. 4%) were complicated with CVD .Compared with non-CVD group ,there were significant rise in age≥65 years ,abnormal fasting blood glucose (FBG) , abnormal 2h postprandial blood glucose (2hPG) , abnormal glycosy-lated hemoglobin A1c (HbA1c) and SBP in CVD group , P＜0.05 or ＜0.01 .Spearman correlation analysis indica-ted that age ,FBG ,2hPG ,DPN ,SBP and HbA1c were significant positively correlated with CVD risk (r＝0.612～0.735 , P＝0.001 all).Multifactor Logistic regression analysis indicated that DPN , abnormal FBG and abnormal 2hPG were independent risk factors for CVD (OR＝1.248～2.023 , P＜0.05 all).Conclusion : Diabetic peripheral neuropathy is one of the independent risk factors for CVD in T2DM patients .Attention should be paid to preven-tion ,screening and early treatment of CVD in these patients in clinic .
