Therapeutic effects of rosuvastatin and atorvastatin on patients with coronary heart disease angina pec-toris and their influence on blood lipids
10.3969/j.issn.1008-0074.2018.02.10
- VernacularTitle:瑞舒伐他汀与阿托伐他汀对冠心病心绞痛患者的疗效及血脂的影响
- Author:
Yan-Hui ZHANG
1
;
Jia-Nong XING
;
Xiu-Juan QI
;
Xiao-Feng LIU
Author Information
1. 河北省唐山市第三医院心内科
- Keywords:
Coronary disease;
Angina pectoris;
Rosuvastatin
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2018;27(2):154-157
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore therapeutic effects of rosuvastatin and atorvastatin on patients with coronary heart disease(CHD)angina pectoris and their influence on blood lipids.Methods:A total of 100 CHD inpatients with sta-ble angina pectoris(SAP)were selected.According to random control table,they were randomly and equally divid-ed into rosuvastatin group and atorvastatin group.Both groups received corresponding lipid-lowering medication based on routine treatment of CHD angina pectoris for four weeks.Clinical and ECG therapeutic effect were ob-served,blood lipid levels were measured before and after treatment,adverse drug reactions were observed and medi-ation cost was recorded in two groups.Results:Compared with atorvastatin group,there were significant rise in clinical and ECG total effective rate[(76% vs.92%),(60% vs.84%)],and significant reduction in mediation cost[(12369.94 ± 231.81)RMB vs.(11784.52 ± 206.97)RMB]in rosuvastatin group,P<0.05 or <0.01. There were no significant difference in blood lipid levels between two groups before and after treatment(P>0.05 all),and all of them were inside normal range.There was no significant difference in incidence rate of adverse drug reactions between two groups(P>0.05).Conclusion:Compared with atorvastatin,rosuvastatin can more significantly prevent onset of CHD angina pectoris, and it's safe,effective,and hospitalization cost is significantly reduction.
