Transcutaneous CO2 and transcutaneous O2 monitoring in the evaluation of neonatal respiratory failure
10.3760/cma.j.issn.2096-2932.2018.06.009
- VernacularTitle:经皮二氧化碳分压及氧分压监测在新生儿呼吸衰竭中的应用
- Author:
Jinglin XU
1
;
Ruiquan WANG
;
Lianqiang WU
;
Dongmei CHEN
Author Information
1. 362000,福建省泉州市儿童医院新生儿科
- Keywords:
Blood gas analysis;
Blood gas monitoring,transcutaneous;
Respiratory insufficiency;
Infant,newborn
- From:Chinese Journal of Neonatology
2018;33(6):437-441
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical value of transcutaneous O2 (TcPO2) and transcutaneous CO2 (TcPCO2) monitoring among infants with respiratory failure.Method From August 2017 to February 2018,neonates with respiratory failure treated with nasal continuous positive airway pressure (NCPAP) or mechanical ventilation (MV) in the neonatal department were prospectively enrolled.At four time points of 30 min,6 h,24 h after respiratory support and before discharged,TcPO2 and TcPCO2 were compared with PaO2 and PaCO2 using the correlation and consistency analysis methods.Result A total of 368 paired samples from 92 infants were collected.The correlations of TcPCO2 and PaCO2 at 30 min,6 h,24 h and before discharged were strong (r =0.790,95 ％ CI 0.656 ～ 0.884;r =0.827,95 ％ CI 0.710 ～ 0.908;r =0.901,95 ％ CI 0.867 ～ 0.932;r =0.905,95 ％ CI0.830 ～ 0.954,P ＜ 0.05).The correlations of TcPO2 and PaO2 at 30 min,6 h,24 h were weak (r =0.629,95％ CI 0.461 ～ 0.767;r =0.638,95％ CI 0.465 ～ 0.793;r =0.739,95 ％ CI 0.619 ～ 0.831),but strong before discharged (r =0.886,95 ％ CI 0.818 ～ 0.934).Conclusion When tissue well perfused,TcPCO2 is an accurate,continuous and noninvasive marker to evaluate the PaCO2 of neonates with respiratory failure.But TcPO2 cannot reflect PaO2 accurately,and the combination of other index of oxygenation should be used.
