Progress in the chemoprophylaxis of neonatal fungal infection

VernacularTitle:药物预防新生儿真菌感染的研究进展
Author: Wenxin DENG ¹ ; Lujun WANG ; Jingyun SHI ; Fangping ZHAO
Author Information

1. 甘肃省妇幼保健院新生儿科
Keywords: Neonate; Fungal; infection; Chemoprophylaxis
From: Chinese Pediatric Emergency Medicine 2018;25(9):695-697,702
CountryChina
Language:Chinese
Abstract: Due to the improvement of infant survival rates,Candidas have been proved to be the third most common pathogen of late-onset sepsis in NICU,and invasive fungal infection of high-risk infants is in-creasing attention. As the diagnosis is difficult,treatment is often delayed,high mortality and severe disability are also caused,it's becoming a research hot spot to assess whether antifungal prophylaxis is beneficial. Now a number of studies have been performed to discuss the prophylactic role of fluconazole and nystatin,but has not yet reached a consensus. This review described the influence of chemoprophylaxis on fungal infection, colonization and drug resistance.