Early diagnosis biomarkers of neonatal necrotizing enterocolitis
10.3760/cma.j.issn.1673-4912.2018.04.016
- VernacularTitle:新生儿坏死性小肠结肠炎早期诊断生物标记物的研究进展
- Author:
Renhui CHEN
1
Author Information
1. 中国医科大学附属盛京医院新生儿科
- Keywords:
Biomarker;
Necrotizing enterocolitis;
Neonate
- From:
Chinese Pediatric Emergency Medicine
2018;25(4):301-305
- CountryChina
- Language:Chinese
-
Abstract:
Necrotizing enterocolitis(NEC) is a serious disease of digestive tract common in prema-ture infants,which is acute onset with high risk of death.Its early clinical symptoms are not typical,and it lacks sensitivity in radiological examination,so it is sometimes unreliable only based on the clinical manifes-tation and imaging results for early diagnosis.Recently,some biomarkers have certain changes in the early onset of NEC,such as intestinal fatty acid binding protein,intestinal trefoil factor,β-glucosidase,fecal calpro-tectin,which have certain significance to guide the clinical treatment and evaluate the severity of NEC.
