Stem cells in orthopedics diseases: existing problems and application prospects
10.3969/j.issn.2095-4344.0513
- VernacularTitle:干细胞在骨科多种疾病治疗中的应用:问题及前景
- Author:
Zhan-Yu WU
1
;
Chuan YE
Author Information
1. 贵州医科大学
- From:
Chinese Journal of Tissue Engineering Research
2018;22(17):2775-2782
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND: Treatment of orthopedics diseases is largely based on reconstruction to restore the normal structure of the human motor system. However, the human body's ability to repair cannot meet clinical requirements for the treatment of some diseases. In order to solve the problem of tissue regeneration in life science, stem cell therapy has emerged in recent years. OBJECTIVE: To summarize the research progress of stem cells in orthopedics diseases. METHODS: A computer-based search of CNKI, WanFang and PubMed databases was performed for relevant articles concerning stem cell therapy for orthopedics diseases published from 2000 to 2017. Representative and innovative results were analyzed in result analysis. RESULTS AND CONCLUSION: Studies have shown that stem cells have advantages in the treatment of diseases involving the bone, cartilage, spinal cord injury, tendon and ligament injury, and degenerative disc disease. However, further investigations with large sample, long-term follow-up and higher evidence level are warranted. Meanwhile, a good understanding of the natural course of diseases is essential to better utilize stem cell therapy in clinical practice. Combination of stem cell therapy with traditional surgery can achieve better outcomes in patients.
