Early versus Late Intravitreal Triamcinolone Acetonide for Macular Edema associated with Branch Retinal Vein Occlusion.
- Author:
Joo Youn OH
1
;
Je Hyun SEO
;
Jae Kyoun AHN
;
Jang Won HEO
;
Hum CHUNG
Author Information
- Publication Type:Original Article ; Controlled Clinical Trial
- Keywords: Branch retinal vein occlusion; Intravitreal triamcinolone; Macular edema
- MeSH: Visual Acuity/drug effects; Triamcinolone Acetonide/*administration & dosage/therapeutic use; Treatment Outcome; Tomography, Optical Coherence; Retinal Vein Occlusion/*complications; Middle Aged; Male; Macular Edema, Cystoid/chemically induced/*drug therapy/physiopathology; Humans; Glucocorticoids/*administration & dosage/therapeutic use; Fovea Centralis/drug effects; Female; Drug Administration Schedule
- From:Korean Journal of Ophthalmology 2007;21(1):18-20
- CountryRepublic of Korea
- Language:English
- Abstract: PURPOSE: To compare the effect of early versus late intravitreal injection of triamcinolone in patients with macular edema due to branch retinal vein occlusion (BRVO). METHODS: Twenty eyes of 20 patients with macular edema from BRVO, including 10 with duration after onset of < or =3 months and 10 with duration of >3 months, were treated using a single intravitreal triamcinolone injection (4 mg/0.1 ml). Best-corrected visual acuity and foveal thickness by optical coherence tomography were measured 1, 3, and 6 months post-injection. RESULTS: In patients that received treatment after a disease duration of < or =3 months, visual acuity and foveal thickness significantly improved from baseline over 6 months of follow-up. However, in those with a duration of >3 months, improvements in visual acuity and foveal thickness, though apparent at 1 month, were not maintained at 3 and 6 months post-triamcinolone. CONCLUSIONS: Intravitreal triamcinolone is more effective in patients with BRVO who are treated earlier.
