Active Surveillance for Favorable-Risk Prostate Cancer: A Short Review.
10.4111/kju.2010.51.10.665
- Author:
Nathan LAWRENTSCHUK
1
;
Laurence KLOTZ
Author Information
1. Department of Urology, University of Toronto, Sunnybrook Health Sciences Centre, Toronto, Canada. laurence.klotz@sunnybrook.ca
- Publication Type:Review
- Keywords:
Needle biopsy;
Outcome assessment;
Prostate neoplasms;
Prostate-specific antigen;
Review
- MeSH:
Biopsy;
Biopsy, Needle;
Humans;
Male;
Mass Screening;
Patient Selection;
Prostate;
Prostate-Specific Antigen;
Prostatic Neoplasms
- From:Korean Journal of Urology
2010;51(10):665-670
- CountryRepublic of Korea
- Language:English
-
Abstract:
Active surveillance is becoming a more widely accepted management strategy in men with low-risk localized prostate cancer. This is in recognition of the knowledge that most men with such cancer are likely to die from other causes. The obvious benefits of active surveillance are reduced morbidity by delaying or avoiding radical gland therapy. These advantages should be balanced against appropriate selection criteria and triggers for moving to radical therapy while on active surveillance. The optimal method by which to identify the small number of men who will progress by use of clinical, biopsy, and imaging data is yet to be defined. Nevertheless, active surveillance is an appealing management option in selected men with prostate cancer and represents a solution to the significant problem of the overdiagnosis of clinically insignificant disease that accompanies prostate-specific antigen (PSA) screening.
