Relationship between ischemia-modified albumin and coronary stenosis
10.7652/jdyxb201804002
- VernacularTitle:缺血修饰性白蛋白与冠状动脉狭窄病变的相关性
- Author:
Ya-Jie FAN
1
;
Yang ZHENG
;
Yang XU
;
Tuo HAN
;
Hong GONG
;
Wei-Dong MA
;
Xiao-Huan LIU
;
Shan JIA
;
Yan-Chao HU
;
Chun-Yan ZHANG
;
Yan ZHANG
;
Cong-Xia WANG
Author Information
1. 西安交通大学第二附属医院心血管内科
- Keywords:
ischemia-modified albumin(IMA);
coronary atherosclerotic heart disease;
coronary angiography(CAG);
albumin(Alb)
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2018;39(4):459-462,478
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between ischemia-modified albumin (IMA) and coronary artery stenosis in patients without myocardial infarction.Methods For this study we consecutively enrolled 345 patients who received coronary angiography (CAG).According to the results,the subjects were divided into coronary stenosis group (232 cases)and control group (113 cases)to investigate the the relationship of IMA and IMA/albumin (IMAr)with coronary stenosis.Results ① The levels of IMA and IMAr in coronary stenosis group were higher than those in control group (P＜0.001).② The IMA and IMAr were higher in single-branch and multi-branch lesion groups than in control group (P＜0.05),whereas there was no significant difference between single-branch lesion group and multi-branch lesion group (P＞0.05).③ In receiver operating characteristics curve analysis,the sensitivity of IMA and IMAr was 64.4% and 78.0%,respectively (AUC:0.653,0.705,P＜0.001)in predicting coronary stenosis.④ Multivariate logistic regression analysis showed that IMAr was an independent risk factor for coronary stenosis in patients without myocardial infarction (OR=73.05,P＜0.001).Conclusion IMA and IMAr are closely correlated with coronary stenosis and have a value in predicting coronary artery stenosis in patients without myocardial infarction.
