A comparative study of patent foramen ovale and white matter lesions in migraine without aura
10.7652/jdyxb201802006
- VernacularTitle:卵圆孔未闭与无先兆偏头痛患者脑白质病变的比较研究
- Author:
Yi-Tong BIAN
1
;
Hui XIE
;
Zhi-Jie JIAN
;
Jun-Jun LI
;
Ning-Ning DING
;
Gang NIU
;
Guo-Gang LUO
;
Jian YANG
Author Information
1. 西安交通大学第一附属医院 医学影像科
- Keywords:
migraine without aura;
patent foramen ovale;
white matter lesion;
magnetic resonance imaging
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2018;39(2):185-189,209
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of patent foramen ovale(PFO)on white matter lesions(WMLs) in migraine without aura(MwoA).Methods Thirty-five patients with MwoA were examined by contrast transcranial Doppler(cTCD)and magnetic resonance imaging(MRI).According to the results of PFO and MRI Flair data,the patients' age,sex and headache characteristics were matched,and the WMLs were compared between the PFO positive group and negative group.Results Seven cases of WMLs were recruited in PFO positive group(19 cases)and the WMLs were distributed in the frontal lobe and/or the parietal lobe.The score ranged from 1 to 7 points.Five cases of WMLs were enrolled in PFO negative group(16 cases)and the WMLs also were distributed in the frontal lobe and/or the parietal lobe.The score ranged from 1 to 3 points.There was no significant difference in WMLs between the groups(P> 0.05).Conclusion White matter lesions in migraine without aura are distributed in the frontal lobe and the parietal lobe,and these findings do not support a relationship between PFO and WMLs.