Comparison of the clinical value of MRI classification system of deep gray matter injury in children with cerebral palsy
10.7652/jdyxb201802004
- VernacularTitle:脑瘫儿童深部灰质损伤MRI分级系统的临床价值比较
- Author:
Heng LIU
1
;
Miao-Miao WANG
;
Xiao-Yu WANG
;
Hui-Fang ZHAO
;
Liang WU
;
Hao-Xiang JIANG
;
Cong-Cong LIU
;
Xian-Jun LI
;
Chao JIN
;
Qin-Li SUN
;
Jing-Wei MA
;
Hui WANG
;
Jian YANG
Author Information
1. 西安交通大学第一附属医院影像科
- Keywords:
cerebral palsy;
deep gray matter;
magnetic resonance imaging(MRI);
gross motor function classi-fication system(GMFCS);
manual ability classification system(MACS)
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2018;39(2):174-178,193
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the reliability of MRI classification and clinical significance of deep gray matter injury(DGMI)in children with cerebral palsy(CP).Methods We made a retrospective assessment of 14 children with gross motor function classification system(GMFCS),manual ability classification system(MACS)and MRI classification system of deep gray matter injury.Based on T2WI,two radiologists worked independently and graded MRI pictures according to three-grading system and four-grading system.To evaluate the reliability of different grading systems,intra-observer and inter-observer agreements were tested by Kappa test.Spearman correlation analysis was performed to analyze the MRI classification system with GMFCS and MACS.Results The Kappa value of the intro-observer and inter-observe agreement of three-grading system was 0.873 and 0.873,respectively (P＜0.001).The Kappa value of the intro-observer and inter-observe agreement of four-grading system was 0.901 and 0.611(P＜0.001).Three-grading system had no significant correlation with GMFCS(r=0.053,P＞0.05)or MACS(r=0.128,P＞0.05).Four-grading system had a significant positive correlation with GMFCS(r=0.605, P＜0.05)and MACS(r=0.779,P＜0.05).Conclusion In the two grading systems,four-grading system is a more repeatable approach for detecting deep gray matter,gross motor function and manual function injuries in children with cerebral palsy.
