Advances in Study on Relationship Between Epithelial Sodium Channel and Inflammatory Bowel Disease
10.3969/j.issn.1008-7125.2018.10.013
- VernacularTitle:上皮钠通道与炎症性肠病关系的研究进展
- Author:
Dandan WANG
1
;
Beibei YANG
;
Chuang GAO
;
Xiaobo DU
;
Li GENG
;
Xuping WANG
;
Baisui FENG
Author Information
1. 郑州大学第二附属医院消化内科 450014
- Keywords:
Epithelial Sodium Channel;
Inflammatory Bowel Disease;
Extracellular Signal-Regulated Kinases;
Tumor Necrosis Factor-alpha
- From:Chinese Journal of Gastroenterology
2018;23(10):634-637
- CountryChina
- Language:Chinese
-
Abstract:
Inflammatory bowel disease (IBD)is an autoimmune disease leading to diarrhea,abdominal pain,and weight loss. The pathogenesis of diarrhea remains unclear,however,increasing evidence has shown that the epithelial sodium channel (ENaC)is associated with diarrhea. ENaC is crucial in the control of sodium homeostasis,extracellular fluid volume,blood pressure. This article reviewed advances in study on relationship between ENaC and IBD.
