Application of Biological Agents in Treatment of Perianal Fistulizing Crohn's Disease
10.3969/j.issn.1008-7125.2018.10.011
- VernacularTitle:生物制剂在克罗恩病合并肛周瘘管治疗中的应用
- Author:
Xiaohan YAN
1
;
Mingming ZHU
;
Xitao XU
;
Zhihua RAN
Author Information
1. 上海交通大学医学院附属仁济医院消化内科 上海市消化疾病研究所 上海市炎症性肠病研究中心 200001
- Keywords:
Crohn Disease;
Perianal Fistula;
Biological Agents;
Therapy
- From:
Chinese Journal of Gastroenterology
2018;23(10):626-629
- CountryChina
- Language:Chinese
-
Abstract:
Perianal fistulizing Crohn's disease (pfCD)often indicates aggressive and refractory phenotype. Two-thirds of the patients with pfCD will relapse,so the treatment is really challenging. Currently,biological agents have made great progress. The application of biological agents such as infliximab brings new hope to the treatment of pfCD. This article reviewed the application of biological agents in treatment of pfCD.