Accurate Understanding of Pathological Profile in Systemic Lupus Erythematosus With Liver Damage
10.3969/j.issn.1008-7125.2018.05.008
- VernacularTitle:正确认识系统性红斑狼疮肝脏受累的病理学谱
- Author:
Ruru GUO
1
;
Liangjing LÜ
Author Information
1. 上海交通大学医学院附属仁济医院风湿科 200001
- Keywords:
Lupus Erythematosus;
Systemic;
Liver Damage;
Pathology;
Diagnosis
- From:
Chinese Journal of Gastroenterology
2018;23(5):293-295
- CountryChina
- Language:Chinese
-
Abstract:
Systemic lupus erythematosus (SLE)is a prototypic autoimmune disease characterized by multisystemic organ involvement and production of multiple autoantibodies. The clinical manifestations of patients varied,ranging from mild joint pain and skin involvement to life-threatening internal organs involvement. In clinical practice,it is not common to have severe liver damage or even fulminant hepatic failure due to SLE disease itself. Liver is not the main organ to be involved in SLE,but abnormal elevation of liver enzyme is common in SLE. Liver biopsy is the gold standard for definite diagnosis. This article summarized the current reports of SLE with liver damage and analyzed the pathological changes of liver lesions due to SLE disease itself for improving the understanding of histopathology profile of SLE complicated with liver damage.
