Difficult Problems and Strategy on Diagnosis and Treatment of Gastroesophageal Reflux Disease
10.3969/j.issn.1008-7125.2018.04.001
- VernacularTitle:胃食管反流病的诊治难点与对策
- Author:
Bin L(U)
1
Author Information
1. 浙江中医药大学附属第一医院消化内科 310006
- Keywords:
Gastroesophageal Reflux;
Diagnosis;
Therapy;
Proton Pump Inhibitors
- From:
Chinese Journal of Gastroenterology
2018;23(4):193-196
- CountryChina
- Language:Chinese
-
Abstract:
Gastroesophageal reflux disease(GERD)is a chronic and recurrent disease with a wide variety of symptoms,often overlapping with functional gastrointestinal disorders,having different response to proton pump inhibitor (PPI)therapy,and facing various challenging for diagnosis and treatment. It is important for improving the diagnosis via knowing well the clinical manifestations of GERD and related diseases,rational using PPI test,upper gastrointestinal endoscopy and ambulatory esophageal pH/impedance monitoring,and understanding the relationship between the symptoms and reflux events. Different strategies of maintenance therapy should be chosen in accordance with patient's condition for decreasing recurrence. Aggressive acid suppressive therapy,inhibiting gastroesophageal reflux and modulating esophageal hypersensitivity are the main treatment methods for patients with poor response to PPI after ruling out the non-GERD causes.
