Commonly Seen Gene Polymorphisms in Inflammatory Bowel Disease
10.3969/j.issn.1008-7125.2018.03.012
- VernacularTitle:炎症性肠病常见基因多态性
- Author:
Wenpeng ZHOU
1
;
Aiping BAI
Author Information
1. 南昌大学第一附属医院消化内科 330006
- Keywords:
Inflammatory Bowel Disease;
Colitis;
Ulcerative;
Crohn Disease;
Polymorphism;
Single Nucleotide;
Genome-Wide Association Study
- From:
Chinese Journal of Gastroenterology
2018;23(3):177-180
- CountryChina
- Language:Chinese
-
Abstract:
Inflammatory bowel disease(IBD),including ulcerative colitis(UC)and Crohn's disease(CD),is a group of chronic and relapsed inflammatory diseases of the intestinal tract. Genetic factors together with immunological, environmental and infectious factors contribute to the pathogenesis of IBD,however,the precise etiology is still uncertain. Susceptibility genes have great impact on the occurrence,development,clinical phenotypes,and even follow-up treatment of IBD,which indicates the significant roles of genetic factors in this disease. In this article,the well-studied and newly found genes related to IBD and their single nucleotide polymorphisms(SNPs)were reviewed.
