Roles of Treg Cells and Th17 Cells in Treatment of Inflammatory Bowel Disease
10.3969/j.issn.1008-7125.2018.02.011
- VernacularTitle:Treg细胞和Th17细胞在炎症性肠病治疗中的作用
- Author:
Xuepei JIANG
1
;
Xiaoli WU
;
Zhiming HUANG
Author Information
1. 温州医科大学附属第一医院消化内科
- Keywords:
Inflammatory Bowel Disease;
T-Lymphocytes,Regulatory;
Th17 Cells;
Therapy
- From:
Chinese Journal of Gastroenterology
2018;23(2):109-112
- CountryChina
- Language:Chinese
-
Abstract:
Inflammatory bowel disease(IBD)is a kind of non-specific intestinal inflammatory disease. The immune imbalance of intestinal mucosa is the main cause of IBD. Regulatory T cells(Treg cells)are important immune-regulatory cells,and helper T cells 17(Th17 cells)participate in host immune defense. The balance between Treg cells and Th17 cells is an important factor to maintain intestinal immune homeostasis. This article reviewed the roles of Treg cells and Th17 cells in the treatment of IBD.