Analysis of Correlation Between Nonalcoholic Fatty Liver Disease and Colorectal Polyps
10.3969/j.issn.1008-7125.2018.02.003
- VernacularTitle:非酒精性脂肪性肝病与结直肠息肉发病的相关性分析
- Author:
Song WANG
1
;
Fang FANG
;
Lei YE
;
Jian CHEN
;
Heng LU
;
Miaofang YANG
;
Fangyu WANG
Author Information
1. 南京军区南京总医院消化内科
- Keywords:
Nonalcoholic Fatty Liver Disease;
Intestinal Polyps;
Retrospective Studies
- From:
Chinese Journal of Gastroenterology
2018;23(2):75-77
- CountryChina
- Language:Chinese
-
Abstract:
Background:Nonalcoholic fatty liver disease(NAFLD)is the liver manifestation of metabolic syndrome,and may be related with the incidence of colorectal polyps. However,studies on the correlation between NAFLD and colorectal polyps are rare. Aims:To investigate the correlation between NAFLD and colorectal polyps. Methods:Clinical data of 130 asymptomatic patients accepted physical examination were retrospectively analyzed. Detection rates of NAFLD and colorectal polyps were evaluated,and the correlations with body mass index(BMI),hs-CRP,triglyceride,low density lipoprotein,total cholesterol,alanine aminotransferase(ALT),glutamyltranspeptidase(GGT)were analyzed. Results:Compared with non-NAFLD patients,the detection rate of colorectal polyps in NAFLD patients was significantly increased (66.3% vs. 40.0%,P=0.003 9),BMI,triglyceride and ALT were significantly increased(P<0.05). However,no significant differences in hs-CRP,low density lipoprotein,total cholesterol and GGT were found between NAFLD and non-NAFLD patients. Compared with non-colorectal polyps patients,the average age of patients with colorectal polyps was higher(P =0.013),and detection rate of NAFLD was significantly increased(72.6% vs. 47.4%,P =0.003 9). However,no significant differences in BMI,hs-CRP,triglyceride,low density lipoprotein,total cholesterol,ALT,GGT were found between colorectal polyps group and non-colorectal polyps group(P>0.05). Conclusions:NAFLD may be closely correlated with the incidence of colorectal polyps.
