The Effects of Phonosurgery for Vocal Fold Nodule Combined with Botulinum Toxin of Type A Injection in Adults
10.3969/j.issn.1006-7299.2018.01.007
- VernacularTitle:手术联合A型肉毒毒素甲杓肌注射治疗成人声带小结的疗效分析
- Author:
Qingxiang ZHANG
1
;
Huiying HU
;
Shuangba HE
;
Guoyan SUN
;
Zhenkun YU
Author Information
1. 东南大学医学院附属南京同仁医院耳鼻咽喉头颈外科 南京 211102
- Keywords:
Vocal cord nodule;
Larynx microsurgery;
Botulinum toxin of type A;
Thyroarytenoid mus-cle injection
- From:
Journal of Audiology and Speech Pathology
2018;26(1):25-28
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of phonosurgery combined with botulinumtoxinof type A in-jection in adults with vocal nodules .Methods A total of 76 adults with diagnosis of vocal nodules were studied in this experiment .They were divided into two group according to the different treatments :the surgery group (n=40) ,and the group with the combined botulinum toxin of type A injection (n=36) .Preoperative and postoperative examinations consisted of electronic laryngoscope ,stroboscopic laryngoscope ,voice assessments of subjective and objective evaluations using GRBAS classification and voice disorder index (VHI) .The evaluation parameters were the longest phonation time (MPT) ,jitter and shimmer and dysphonia severity index (DSI) .The results from the two groups were compared .Results There were 5 cases cured ,28 cases improved and 7 cases of now effects in the surgery group .The effective rate was 82 .5％ .There were 30 cases cured and 6 cases improved in the combined in-jection group with the effective rate of 100％ .There were 22 cases with good glottis closure and 18 cases with incom-plete closure in the surgery group postoperatively ;in the combined injection group ,30 cases glottis closed well and 6 cases still closed incompletely .The differences of postoperative VHI ,MPT ,jitter ,shimmer and DSI in addition to G were significant different between the two groups .Conclusion Phonosurgery combined with botulinum toxin of type A injection is an effective way for the treatment of vocal fold nodules in adults .
