Protective Effect of Breastfeeding on the Occurrence of Type 2 Diabetes in Women with Gestational Diabetes Mellitus
10.3870/j.issn.1672-0741.2018.02.022
- VernacularTitle:母乳喂养对妊娠糖尿病患者罹患2型糖尿病的保护性效应
- Author:
Xiaohong YOU
1
;
Xueming HUANG
Author Information
1. 西南医科大学附属中医院妇产科
- Keywords:
gestational diabetes mellitus;
lactation;
type 2 diabetes;
protective effect
- From:
Acta Medicinae Universitatis Scientiae et Technologiae Huazhong
2018;47(2):236-239
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the protective effect of breastfeeding on the occurrence of type 2 diabetes mellitus(T2DM) in women with gestational diabetes mellitus(GDM).Methods A total of 660 GDM women were enrolled in this prospective co-hort study.Blood glucose levels were detected 6 to 9 weeks after delivery(baseline)and then on a year basis for 2 years.The re-lated data of T2DM were collected.Stata 12.0 and SPSS 20.0 were used for data analysis.Results In total,615 women completed the follow-up tests.Seventy-eight(12.7%)were diagnosed as having T2DM,and the incidence rate was 5.919/(1000 person·month) .Twenty-four in formula feeding group were diagnosed as having T2DM,and the incidence rate was 8.153/(1000 person· month).Forty-two in mixed feeding group were diagnosed with T2DM,and the incidence rate was 5.657/(1000 person · month).Twelve in breastfeeding group were diagnosed as having T2DM,and the incidence rate was 4.091/(1000 person· month).Weibull regression model analysis showed that after adjustment of confounding factors,the hazard ratios in mixed feed-ing group and breastfeeding group versus formula feeding group were 0.52(95% CI:0.28~0.89)and 0.43(95% CI:0.23~0.82),respectively(P=0.023).Conclusion Breastfeeding can effectively reduce the risk for T2DM in GDM women.It is effec-tive to control the occurrence of T2DM by strengthening the follow-up of GDM women and postpartum weight control.
