Research progress of Eph receptor family in the lung cancer and its potential application as targets of lung cancer
10.11904/j.issn.1002-3070.2018.02.015
- VernacularTitle:Eph受体家族在肺癌中的研究进展及作为肺癌治疗靶点的可能
- Author:
Jiawen HE
1
Author Information
1. 哈尔滨医科大学附属肿瘤医院
- Keywords:
Eph;
Ephrin;
Lung cancer
- From:
Practical Oncology Journal
2018;32(2):164-168
- CountryChina
- Language:Chinese
-
Abstract:
The Eph receptors and their ligand Ephrins are closely associated with angiogenesis,cell migration,neuronal local-ization and embryonic development.More and more studies have shown that the Eph receptor and Ephrins are involved in the occur-rence and development of various cancers.In this article,we will focus on the Eph receptor family involved in the formation and devel-opment of lung cancer and metastasis,drug resistance and other mechanisms as well as their potential as targeted therapy of lung canc-er.
