Regulative mechanism of long non-coding RNA in gastric cancer and its role in traditional Chinese medicine
10.11904/j.issn.1002-3070.2018.01.009
- VernacularTitle:长链非编码RNA在胃癌中的调控机制及中药对其作用的研究概况
- Author:
Jiahui YU
1
;
Xuan LIU
;
Qi LI
;
Ye LU
Author Information
1. 上海长征医院中医科
- Keywords:
Long noncoding RNA;
Gastric Cancer;
Chinese Medicine;
Review
- From:
Practical Oncology Journal
2018;32(1):47-52
- CountryChina
- Language:Chinese
-
Abstract:
Long non-coding RNA(LncRNA)is a class of RNA that cannot encode translated proteins with more than 200 nucleotides in length.It can be involved in the regulation of X chromosome silencing,chromatin modification,transcriptional activa-tion,transcriptional interference and other regulatory processes by binding to DNA,RNA or proteins.In recent years,more and more studies have confirmed that LncRNA plays an important role in the occurrence,development,invasion and metastasis of gastric cancer. At the same time,many studies have demonstrated LncRNA as the target of traditional Chinese medicine for the development and pro-gression of anti-gastric cancer.This review introduces the mechanism of LncRNA in the development and progression of gastric canc-er,and as a target for traditional Chinese medicine treatment prospects.
