Research progress on the relationship between microRNA-196a and tumor
10.11904/j.issn.1002-3070.2018.01.008
- VernacularTitle:microRNA-196 a与肿瘤相关性的研究进展
- Author:
He XIN
1
;
Chuanzhuo WANG
Author Information
1. 中国医科大学附属盛京医院
- Keywords:
miR-196a;
Tumor;
microRNA
- From:
Practical Oncology Journal
2018;32(1):42-46
- CountryChina
- Language:Chinese
-
Abstract:
As a member of the miRNA family,microRNA-196a(miR-196a) has received much attention in recent years. MiR-196a not only plays an important regulatory role in various biological processes, but it also shows that miR-196a also func-tions as oncogene in the tumorigenesis and progression. In recent studies, miR-196a is high expression in the serum, tissues and cells of patients with cancer,and can promote tumor cell proliferation,invasion and metastasis,inhibit tumor cell apoptosis and en-hance tumor drug resistance. In this paper,we reviewed the research progress on the correlation between miR-196a and tumor based on the latest reports at domestics and abroad.