Efficacy of early cold budesonide atomization inhalation on postoperative sore throat following double-lu-men endotracheal intubation
10.3969/j.issn.1006-5725.2018.12.036
- VernacularTitle:拔管即刻布地奈德低温雾化吸入对双腔气管导管插管后咽部并发症的影响
- Author:
Qi CHEN
1
;
Xuejiao ZHONG
;
Kaihong HU
;
Lin LAN
;
Bin YANG
Author Information
1. 重庆大学附属肿瘤医院/重庆市肿瘤研究所麻醉科
- Keywords:
cold atomization inhalation;
budesonide;
sore throat;
double-lumen endotracheal
- From:
The Journal of Practical Medicine
2018;34(12):2065-2069
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy of early controlled cold atomization inhalation of budesonide in the treatment of post-operative sore throat (POST) after double-lumen endotracheal intubation. Methods A total of 105 ASAⅠ~Ⅲpatients having POST after thoracic surgery with double-lumen endotracheal intubation were randomly divided into three groups(n = 35 each). The patients in the control group were treated with atomization inhalation of 12 mL 20℃saline(Group C)and those in the observation groups were treated with 10 mL 20℃saline plus 2 mL(1 mg)budesonide(Group R)or 10 mL 0℃saline plus 2 mL(1 mg)budesonide (Group L)for 15 minutes immediately after extubation. The 4-score scale was used to evaluate sore throat,dry throat,hoarseness and swallowing difficulty 1,2,6 and 24 h after the extubation and QoR-40 scale to assess post-operative recovery at 24 h. Results The scores of sore throat and dry throat were significant lower in group L than those in group C(P < 0.05)at 1,2 and 24 h and the score of swallowing difficulty(dysphagia)was also signifi-cant relieved at 1,6 and 24 h after the extubation in group L. Furthermore,the score of sore throat was significant lower in group L than that in group R(P<0.05)at 1 h. There were no significant differences of hoarseness in three groups(P > 0.05). The total score of QoR-40 scale was the significantly highest in group L than that in group C and group R(P<0.05)24 h postoperatively. Conclusion Cold atomization inhalation of budesonide immediately after the extubation of double-lumen endotracheal can alleviate POST and bring more benefits to patients which help to enhance the recovery after throracic surgery.
