Clinical effect of polymer-free sirolimus-eluting Nano stent on patients with coronary artery stenosis
10.3969/j.issn.1006-5725.2018.12.030
- VernacularTitle:无载体含药物洗脱支架治疗冠状动脉狭窄的临床疗效
- Author:
Xinjun CHEN
1
;
Ruolong ZHEN
;
Fengjiao HUANG
;
Zengxin YANG
;
Zhuowen XU
;
Weizhang LI
;
Hua ZHANG
Author Information
1. 东南大学医学院附属江阴医院心内科
- Keywords:
coronary stenosis;
polymer-free sirolimus-eluting;
Nano stent;
endeavor resolute stent;
intravascular unltrasound
- From:
The Journal of Practical Medicine
2018;34(12):2042-2045
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the safety and effectiveness of polymer-free sirolimus-eluting Nano stent in patients with unstable angina pectoris. Methods Three hundred and twenty-one patients with unstable angina pectoris were divided into Nano stent group(group A,n=157)and Endeavor resolute stent group(group B,n=164). The cardiovascular events were compared postoperative 12 months. The minimal intima cavity area and mini-mum bracket section area and neointimal area were compared postoperative 12 months by intravascular unltrasound (IVUS). Results There were 7 cases of cardiovascular events in group A and 6 in group B postoperative 12 months(P=0.727)and 2 patients in group A and 3 in group B were re-implanted stent because of restenosis post-operative 12 months(P=0.672). The neointimal area were(0.31 ± 0.11 mm2)in group A and(0.29 ± 0.12 mm2) in group B postoperative 12 months(P = 0.985). The minimal intima cavity area(P = 0.921)and the minimum bracket section area(P=0.934)were narrower postoperative 12 months than immediately after the operation in two groups. Conclusion With less cardiovascular events and being safe and reliable,the clinical effect of polymer-free sirolimus-eluting Nano stent implantation is similar to that of Endeavor resolute stent implantation.
