Effect of 3D laparoscopic hepatectomy in glissonian approach for hepatocellular carcinoma on the cellular immune function
10.3969/j.issn.1006-5725.2018.12.020
- VernacularTitle:3D腹腔镜Glisson蒂横断式肝切除术治疗肝癌对机体细胞免疫功能的影响
- Author:
Zhaoshan FANG
1
;
Jian YANG
;
Jue PANG
;
Wenying LIU
;
Zhi ZHANG
;
Jie RUAN
;
Hai HUANG
Author Information
1. 南宁市第一人民医院暨广西医科大学第五附属医院
- Keywords:
hepatocellular carcinoma;
3 D laparoscopy;
cellular immune function;
glissonian;
liver resection
- From:
The Journal of Practical Medicine
2018;34(12):2004-2006,2011
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the effects of 3D laparoscopic hepatectomy (3D-LH) and open hepatectomy(OH)in glissonian access for hepatocellular carcinoma(HCC)on postoperative immunosuppression by analyzing cellular immune function. Methods During January 2014 to December 2017,sixty patients randomly scheduled to undergo hepatectomy were divided into 3D-LH group and OH group,with 30 patients in each group. All patients' peripheral blood was sampled to measure cell-mediated-immunologic markers(CD4+,CD8+T cell) before operation and in the mornings of the 1st,7thday after surgery. The effects of different operative methods on cellular immune function in patients organism were investigated. Results The decreased level in 3D-LH group was less than that in OH group in postoperative 1stday. The improvement in the 3D-LH group was more faster than that in the OH group on postoperative 7thday. There was statistical significance between the two groups(P<0.05), respectively. Conclusion When compared to open hepatectomy ,3D laparoscopy liver resection in glissonian approach for HCC,less effects in cellular immune function.
