The application value of DNA hybridization probe test in the diagnosis of bacterial vaginosis and vulvovagi-nal candidiasis
10.3969/j.issn.1006-5725.2018.10.034
- VernacularTitle:核酸杂交检测在细菌性阴道病及外阴阴道假丝酵母菌病诊断中的应用价值
- Author:
Tian LI
1
;
Xiaomao LI
;
Jie DING
;
Min HUANG
;
Ye YU
Author Information
1. 中山大学附属第三医院 广州 510630
- Keywords:
vaginitis microbiological test;
DNA hybridization probe test;
bacterial vaginosis;
vulvo-vaginal candidiasis
- From:
The Journal of Practical Medicine
2018;34(10):1712-1715
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the sensitivity and specificity of DNA hybridization probe test(Af-firm VPIII) in the identification related microorganisms of bacterial vaginosis(BV),vulvovaginal candidiasis (VVC). Methods Vaginal secretion were detected in 103 patients with symptom and sign of vaginitis in the out patient department. According to Nungent score,the fungal culture as the gold standard. BV blue reagent assay and wet mount microscopy as a common detection method,evaluated the sensitivity and specificity of Affirm VPIII. Results Compared with the Nungent score,the sensitivity and specificity of Affirm VPIII were 98% and 96.2%. Compared with the fungi culture,the sensitivity and specificity of Affirm VPIII were 89.4% and 98.3%. Conclusion Affirm VPIII has high sensitivity and specificity which can identify pathogenic microorganisms of BV,VVC,especially in BV diagnosis.
