Application of BIS-guided TCI with propofol and remifentanil for interventional embolization therapy of cerebral aneurysm
10.3969/j.issn.1006-5725.2018.10.032
- VernacularTitle:BIS监测下靶控输注异丙酚复合瑞芬太尼在全麻脑血管动脉瘤介入栓塞治疗中的临床观察
- Author:
Yan YANG
1
;
Quan HU
Author Information
1. 湖北省武汉市江夏区第一人民医院麻醉科 武汉 430200
- Keywords:
BIS;
propofol;
interventionai embolization;
general anesthesia
- From:
The Journal of Practical Medicine
2018;34(10):1705-1707,1711
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of BIS-guided TCI with propofol and remifentanil for inter-ventional embolization therapy of cerebral aneurysm. Methods Sixty-eight patients of both sexes undergoing elec-tive cerebral aneurysm embolization were randomly divided into two groups:Group A(TCl with propofol and remi-fentanil),Group B(BIS-guided TCl with propofol and remifentanil). Group A was adjusted the concentration of propofol depending on clinical experience and hemodynamic changes,while group B adjusted the concentration of propofol depending on BIS which was maintained between 45 to 60. The total anesthesia time and dosage of propo-fol,duration of recovery and extubation,the incidence of restlessness and hypoxemia at extubion were recorded. In-traoperative awareness and incidence of nausea and vomiting were also recorded as postoperative visiting after 24 hours. Results In comparison two groups,The total amount of propofol in group B decreased obviously(P <0.05),duration of recovery and extubation of group B was shorter(P < 0.05). The recovery of consciousness,tid-al volume and respiratory rate of group B was faster than others. Incidence of hypoxemia was lower in group B(P <0.05). Conclusion BIS-guided TCI with propofol and remifentanil for interventional,which can improve the sur-gical safety and anesthetic accuracy,is suitable for interventional embolization therapy of cerebral aneurysm.
