Clinical pathology characteristics and prognostic analysis in 23 cases of breast solid papillary carcinoma
10.3969/j.issn.1006-5725.2018.10.004
- VernacularTitle:乳腺实性乳头状癌临床病理特征及预后分析
- Author:
Wenjing CHEN
1
;
Jiangyu ZHANG
;
Zhongyang CHEN
;
Kunhe WU
;
Hongyi GAO
;
Huijuan LIN
;
Jian WANG
Author Information
1. 广东省妇幼保健院
- Keywords:
breast neoplasm;
solid papillary carcinoma;
neuroendocrine;
immunophenotpe;
dif-ferential diagnosis
- From:
The Journal of Practical Medicine
2018;34(10):1594-1597
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical pathological characteristics of breast solid papillary carcino-ma(SPC). Methods The clinical manifestation,pathology morphology,immunohistochemical characteristics and prognosis of 23 cases with SPC was reviewed. Results There were 16 cases with nipple discharge as the chief com-plaint while 7 cases were mass. 10 cases of ultrasonic examination showed 6 cases(60%)were above BI-RADS grade 4 while 8/13 in X-ray examination. In 8 cases of SPC with invasion,5 cases were luminal A and 3 cases were lumi-nal B. There were no significant differences in the mean age,mean diameter of the mass,neuroendocrine markers (CgA and Syn)and proliferation marker Ki67 between in situ SPC group and invasive SPC group(P > 0.05). The difference between P63 and CK5/6 was statistically significant(P = 0.001,P = 0.019). No recurrence was found in 21 patients. Conclusions SPC is a rare type of breast cancer with good prognosis. Imaging and ductosco-py are easy to make under-diagnosis while pathology is likely to make misdiagnosis,therefore clinical pathologists should pay more attention so as to treat it more accurately.
