Early intervention for severe stenosis of non-infarct related artery in patients with acute ST-segment elevation myocardial infarction and multi-vessel disease
10.3969/j.issn.1006-5725.2018.09.025
- VernacularTitle:急性ST段抬高性心梗多支病变患者急诊介入术后早期干预重度狭窄非梗死相关冠脉的临床研究
- Author:
Guizhou MA
1
;
Ronghe XU
;
Ping CHEN
;
Zhixiong CAI
;
Zhidan ZHU
;
Shaomin CHEN
;
Jianqiang HUANG
;
Ying WANG
;
Wenliang WANG
Author Information
1. 广东省汕头市中心医院心内科 广东汕头 515031
- Keywords:
acute ST-segment elevation myocardial infarction;
multi-vessel disease;
percutaneous coronary intervention;
early intervention
- From:
The Journal of Practical Medicine
2018;34(9):1508-1512
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical feasibility and safety of early intervention for severe stenosis of non-infarct related artery(non-IRA)in patients with acute ST-segment elevation myocardial infarction(STEMI) and multi-vessel disease(MVD)after successful primary percutaneous coronary intervention(PCI)for infarct-asso-ciated artery(IRA). Methods From May 1st,2011 to December 30th,2016,165 patients with STEMI and MVD were enrolled in our study. After the completion of primary PCI in IRA ,75 patients still in the hospital agreed to undergo a second staged PCI in severe stenosis of non-infarct arteries. We analyzed the in-hospital adverse events ,the length of hospital stay and clinical outcomes during the follow-up in the study population. Results There was no significant difference in the incidence of adverse events between the two groups during hos-pitalization. However,compared to patients treated with the IRA-only PCI,those treated with early intervention for severe stenosis of non-IRA was associated with greater benefits for clinical outcomes(including rehospitalization for heart failure,rehospitalization for ACS,recurrent angina pectoris,necessity for reintervention)during the follow-up except for the all-cause mortality. Conclusion Early intervention for severe stenosis of non-IRA is a feasible and safe procedure in patients with acute STEMI and MVD after successful primary PCI.
