Relationship between QT interval(QT)and metabolic syndrome
10.3969/j.issn.1006-5725.2018.09.015
- VernacularTitle:QT间期与代谢综合征的相关性
- Author:
Shuo HAN
1
;
Yuanzhe JIN
;
Xiaohong ZHANG
;
Zhiying DUAN
;
Yingzi LIN
;
Jing LIU
;
Donghui ZHOU
;
Qi WANG
;
Jingru WANG
;
Guofeng WANG
;
Donghan ZHENG
Author Information
1. 中国医科大学附属第四医院心血管内科 沈阳 110032
- Keywords:
QT interval;
corrected QT interval;
metabolic syndrome
- From:
The Journal of Practical Medicine
2018;34(9):1468-1471
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate correlation between QT interval(QT),corrected QT interval(QTc) and metabolic syndrome(MS). Methods Residents who participated in our survey concerning atherosclerosis and related diseases conducted in Shenyang were included. They accomplished questionnaire,physical examination, laboratory tests and electrocardiography test. We divided them into MS group and non-metabolic syndrome (NMS)group according to International Diabetes Federation(IDF)diagnostic criteria for MS. QT interval was measured from the standard 12-lead electrocardiogram. QTc was calculated by using Bazett and Fridericia equations. We analyze correlation of QT ,QTc and MS. Results A total of 739 residents who were 35~64 years old were included. Individuals with MS had longer QTcB and QTcF than NMS group[(415.8 ± 31.9)ms vs.(410.1 ± 32.1)ms, (407.2± 29.1)ms vs.(402.6 ± 28.8)ms,P<0.05]. The more the number of abnormal MS parameters they had, the longer the QT,QTcB and QTcF they had. Regression analysis showed that QT was associated with serum potassium,smoking,blood glucose,and LDL,and QTcB and QTcF were associated with hypertension,waist circumference and blood potassium. Conclusions MS is associated with corrected QTc. Careful ECG monitoring among persons with MS for early detection of a long corrected QT interval may prevent severe and often fatal arrhythmias or sudden death.
