The diagnostic value of nuclide renal dynamic imaging in early renaldamage in elderly essential hyperten-sion
10.3969/j.issn.1006-5725.2018.08.037
- VernacularTitle:99mTc-DTPA肾动态显像在老年高血压早期肾损害中的诊断价值
- Author:
Jing LI
1
;
Wenjun CHENG
;
Yongzhe HAO
;
Yu ZHANG
;
Xuemei WANG
Author Information
1. 内蒙古医科大学附属医院老年病科 呼和浩特010050
- Keywords:
renal dynamic imaging;
essential hypertension;
glomerular filtration rate;
urinary mi-croalbuminuria;
early renal damage
- From:
The Journal of Practical Medicine
2018;34(8):1372-1375
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the diagnostic value of 99mTc-DTPA nuclide renal dynamic imaging in early renal damage in elderly essential hypertension(EH). Methods Among the elderly patients with essential hypertension who were enrolled in our hospital. 86 patients were enrolled as the study subjects. They were divided into two groups according to the results of 24-hour urinary microalbuminuria(MA):MA negative(A) group and MA posistive(B) group.Meanwhile,20 elderly healthy persons were selected as the control group. 99mTc-DTPA re-nal dynamic imaging was performed in all subjects to detect couple glomerular filtration rate(GFR),the peak time(TP),half emptying time(T1/2) and ration of 20 min and peak phase kidney radioactivity count(T20/P%).At the same time,MA,serum cystatin C(Cys-C),surem creatinine(SCr) and blood urea nitrogen(BUN) were de-tected and compared with three groups. Rusults(1)The positive rate of early renal damage with 99mTc-DTPA nu-clide renal dynamic imaging method was significantly higher than those of two later methods(P < 0.01).(2)The levels of GFR,TP,T1/2,and T20/P% in group A were significantly higher than those in the control group and those in group B significantly higher than those in group A(P<0.05).(3)The levels of MA and Cys-C in group A was sig-nificantly higher than that of the control group,and those in group B significantly higher than that of group A(P<0.05).In comparisons of SCr and BUN among the three groups,the results had no significant difference. Conclu-sion 99mTc-DTPA nuclide renal dynamic imaging can early detect the renal damage in elderly EH patients,and it has better clinical value.
