Effects of different anesthesia levels on perioperative cerebral oxygen metabolism and postoperative cogni-tive function in elderly patients
10.3969/j.issn.1006-5725.2018.08.029
- VernacularTitle:不同麻醉深度对老年患者围术期脑氧代谢及术后认知功能的影响
- Author:
Lan KONG
1
;
Yunfei ZHANG
Author Information
1. 郑州大学附属肿瘤医院麻醉科 郑州450008
- Keywords:
gastric cancer;
depth of anesthesia;
elderly patients;
cerebral oxygen metabolism;
postoperative cognitive dysfunction
- From:
The Journal of Practical Medicine
2018;34(8):1339-1342
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of different levels of anesthesia on perioperative cerebral oxygen metabolism and postoperative cognitive function in the elderly patients. Methods One hundred elderly pa-tients receiving gastric cancer surgery were divided into two groups:group D(BIS value 30-39) and group L(BIS value 50-59). Blood samples were collected at T0,T1,T2,T3 and T4. Da-jvO2 and CERO2 were calculated at the same time.MMSE score was recorded at the time point of 1,3 and 7 d after operation.Results Compared with the T0,Da-jvO2 and CERO2 were both decreased in the two groups at T2-T4(P<0.05).Compared with the group L, the group D were decreased more obviously(P < 0.05). Compared with preoperative score,MMSE score was de-creased at the time point of 1,3d in the group L as well as 1d in the group D(P<0.05).Compared with the group L,group D was significantly increased at the time point of 1 and 3 d(P < 0.05). Conclusion BIS value was maintained at 30-39 can decrease perioperative cerebral oxygen metabolism and improve postoperative cognitive function in the elderly patients.
