Clinical significance of H-FABP,hs-CRP and Hcy in patients with atrial fibrillation and chronic heart fail-ure
10.3969/j.issn.1006-5725.2018.08.026
- VernacularTitle:慢性心力衰竭合并心房颤动患者心型脂肪酸结合蛋白、超敏C反应蛋白及同型半胱氨酸水平的变化
- Author:
Yuhui LIN
1
;
Wenjun DAI
;
Xiaoqing HE
Author Information
1. 广州医科大学附属第三医院心内科 广州510150
- Keywords:
atrial fibrillation;
heart type-fatty acid binding protein;
hypersensitive C-reactive pro-tein;
homocysteine
- From:
The Journal of Practical Medicine
2018;34(8):1327-1329,1334
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the level changes and clinical value of serum H-FABP,hs-CRP and Hcy in patients with atrial fibrillation(AF)and chronic heart failure(CHF).Methods 120 patients with AF and CHF were chosen as the observation group,100 patients with sinus rhythm were chosen as the control.The levels of H-FABP,hs-CRP and Hcy of the two groups were compared.H-FABP,hs-CRP and Hcy levels were also compared in the different subgroups divided according to the cardiac function.Risults Compared with the control group,the levels of H-FABP,hs-CRP and Hcy in patients with atrial fibrillation were significantly higher(P<0.05).The lev-els of H-FABP,hs-CRP and Hcy in the observation group were higher than those in the control group in the same cardiac function subgroup(P < 0.05). Conclusion The elevation of the level of H-FABP,hs-CRP and Hcy are closely related to the occurrence and maintenance of atrial fibrillation and the damage of myocardial cells,and it was related with the severity of cardiac function.