Correlation between dual source CT dual energy imaging indices,microvessel density,vascular endotheli-al growth factor and lymphatic involvement in lung cancer
10.3969/j.issn.1006-5725.2018.06.036
- VernacularTitle:肺癌双能量成像、微血管密度和血管内皮生长因子与淋巴结转移的关系
- Author:
Yan GU
1
;
Chongchang MIAO
;
Gang YUAN
;
Zongsheng WANG
;
Ying ZHOU
Author Information
1. 徐州医学院附属连云港市第一人民医院放射科 江苏连云港222002
- Keywords:
lung cancer;
pathology;
lymphatic metastasis;
tomography X-ray computed
- From:
The Journal of Practical Medicine
2018;34(6):1019-1022
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the correlation between dual energy imaging indices,microvessel densi-ty(MVD),vascular endothelial growth factor(VEGF)and lung cancer lymph nodes metastasis and its practical sig-nificance by applying dual source CT(DSCT)dual energy imaging.Methods 62 cases of non-small cell lung can-cer(NSCLC)were underwent DSCT dual energy imaging and divided into groups with and without lymph node me-tastasis according to the results of pathology.The expressions of MVD and VEGF were detected as well.All the indi-ces were compared between the two groups. Results(1)The differences between the lung cancer lymph node groups in the iodine concentration,normalized iodine concentration(NIC),spectrum curve of arterial phase,MVD and VEGF were statistically significant(P<0.05).(2)The iodine concentration,NIC and spectrum curve of arte-rial phase were positively correlated with MVD and VEGF.Conclusion Iodine concentration,NIC,and spectrum curve of arterial phase of DSCT dual energy imaging can be regarded as part of the important indices for preopera-tive diagnosis of lymph node metastasis of NSCLC.
