Expression and relationship of PRL-3,tumor associated macrophags and lymphangiogenesis in papillary thyroid carcinoma
10.3969/j.issn.1006-5725.2018.06.028
- VernacularTitle:甲状腺乳头状癌中PRL-3表达与肿瘤相关巨噬细胞及淋巴管生成的相关性
- Author:
Zhenhua SUN
1
;
Huaping JIANG
;
Wenhua TAO
Author Information
1. 江苏大学附属医院甲乳外科 江苏镇江212000
- Keywords:
papillary thyroid carcinoma;
phosphatase of regenerating liver-3;
tumor associated macro-phages;
lymphangiogenesis
- From:
The Journal of Practical Medicine
2018;34(6):987-990
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship of PRL-3,tumor associated macrophages and lym-phangiogenesis in papillary thyroid carcinoma. Methods SP immunohistochemistry was used to study the levels of PRL-3,CD68,and D2-40 in papillary thyroid carcinoma and thyroid adenoma.Results The positive expression rates of PRL-3,CD-68 and D2-40 were higher in papillary thyroid carcinoma than those in thyroid adenoma (P < 0.01). High PRL-3,CD-68 or D2-40 was associated with lymphatic metastasis in patients with papillary thyroid carcinoma(P<0.01).Conclusion The expression levels of PRL-3,CD-68 and D2-40 are positively cor-related in papillary thyroid carcinoma,and they are related to invasion and lymphangiogenesis of papillary thyroid carcinoma.
