Effects of inverse ratio ventilation on pulmonary function and cerebral oxygen saturation in elderly pa-tients with single lung ventilation
10.3969/j.issn.1006-5725.2018.05.029
- VernacularTitle:反比通气对单肺通气老年患者肺功能和脑氧饱和度的影响
- Author:
Yapeng LI
1
,
2
;
Longjian YAN
;
Jie CHEN
;
Gongjian LIU
Author Information
1. 徐州医科大学 江苏徐州 221002
2. 徐州医科大学附属医院麻醉科 江苏徐州 221006
- Keywords:
inverse ratio ventilation;
one-lung ventilation;
elderly patients;
pulmonary function;
cerebral oxygen saturation
- From:
The Journal of Practical Medicine
2018;34(5):814-816,819
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of inverse ratio ventilation on pulmonary function and ce-rebral oxygen saturation in elderly patients with single lung ventilation.Methods Sixty patients scheduled for elec-tive radical resection of esophageal cancer were divided into 2 groups(n=30 for each group)using a random num-ber table:the experiment group(group A)and the control group(group B). During the two lung ventilation,the ventilator parameters were set as tidal volume(VT)7 mL/kg,inspiratory to expiratory ratio 1:2. During one lung ventilation,the I:E ratio was 1.5:1 in the group A and 1:2 in the group B. At 15 min after two lung ventilation (T1),20 min after one lung ventilation(T2),60 min after one lung ventilation(T3)and 15 min after restarting two-lung ventilation(T4),the blood gas analysis was measured and recorded for the hemodynamics,respiratory me-chanics index and cerebral oxygen saturation respectively. Results Compared with the B group,the Ppeak and VD/VT at T2~T4in the group A were lower while PaO2,Pmean and Cdyn were higher(P<0.05).During one lung ventilation,the incidence of rSO2< 50% or rSO2decreased more than 20% in the group A was lower than that in the group B(P<0.05).The PaO2,Cdyn and rSO2of the two groups at T2~T4were significantly lower and Ppeak, Pmean,PaCO2,VD/VT were significantly higher than the baseline(T1)(P < 0.05). Conclusion During one-lung ventilation,prolonged inspiratory time can improve pulmonary function and lung compliance without increas-ing peak airway pressure,reduce the decline of rSO2 at the same time.