Clinical study of dexmedetomidine in early goal-directed sedation in patients with septic shock
10.3969/j.issn.1006-5725.2018.04.028
- VernacularTitle:右美托咪定对感染性休克患者早期目标导向镇静方案的临床研究
- Author:
Dekai LIU
1
;
Weizhong ZENG
;
Shuanghua WU
;
Yiqian ZENG
;
Jing ZENG
;
Suna PENG
Author Information
1. 株洲市中心医院重症医学科 湖南株洲412007
- Keywords:
dexmedetomidine;
early goal directed sedation;
septic shock;
midazolam
- From:
The Journal of Practical Medicine
2018;34(4):634-637
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficacy and safety of early goal-directed sedation with dexme-detomidine in patients with septic shock.Methods This study is selected from August 2015 to December 2016 in our department 70 patients receiving treatment of septic shock,and through random sample table method divided into the control group and the study group two,there were 32 cases in control group,the control group selected ob-ject according to the conventional sedation treatment,namely the application of midazolam extraction treatment, the study group of 38 patients with septic shock in patients with application of dexmedetomidine sedation,analysis and application of different sedation method analysis of two groups of patients with septic shock. The efficacy and safety of observation and etc. Results Two groups of patients with different treatment methods,The onset time of the study group of patients with septic shock after sedation,h recovery time and time of mechanical ventilation was obviously better than the control group,the effect of difference(P < 0.05),has significant research value. Conclusions For patients with septic shock early goal orientation selection and application of sedation of dexme-detomidine can play a better effect,the more safe and effective,sedation score is high,it is worth of application in clinical treatment.
