1H-MRS magnetic resonance spectroscopy in evaluating the severity and prognosis in patients with brain stem injury
10.3969/j.issn.1006-5725.2018.03.031
- VernacularTitle:1H-MRS磁共振波谱分析在脑干损伤患者伤情及预后评判中的应用
- Author:
Heping ZHOU
1
;
Xinsheng CHEN
;
Zhengsheng SHI
;
Zhengjiang ZHA
;
Jun WANG
;
Peng ZHAO
;
Min CHEN
Author Information
1. 安徽医科大学附属安庆医院神经外科 安徽安庆246003
- Keywords:
brain stem injury;
magnetic resonance spectroscopy;
prognosis
- From:
The Journal of Practical Medicine
2018;34(3):464-467
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the role of magnetic resonance spectroscopy in evaluating the severity and prognosis of patients with brain stem injury. Methods A total of 45 patients with brain injury (the study group)and 10 healthy people(the control group)were retrospectively analyzed in Affiliated Anqing Hospital,Anhui Medical University during March 2015 to October 2016 using magnetic resonance spectroscopy.The NAA/Cr,NAA/Cho and Cho/Cr value in brain stem were analyzed. The clinical severity score (GCS) and Glasgow outcome scale (GOS)were also analyzed in our study. Results Compared with the normal group,patients in the study group had lower NAA level, NAA/Cho value but higher Cho/Cr value (P < 0.05). The severer the injury, the more obvious in NAA peak decrease. Cho peak increased and NAA/Cho ratio decreased. NAA/Cho, NAA/Cr and Cho/Cr values in the group with good prognosis were similar to those in the normal control group, but significantly different to the group with poor prognosis (P < 0.05). NAA/Cr, NAA/Cho and Cho/Cr values correlates with GOS in patients with brain stem injury. Conclusions Magnetic resonance spectroscopy can be used to measure the metabolic status of patients with brain stem injury,which is of great significance in the evaluation the severity of brain stem injury and prognosis.
