Relationship between left ventricular hypertrophy and galactose 3 and microalbuminuria in elderly patients with hypertension

VernacularTitle:老年高血压病患者半乳糖凝集素3及尿微量白蛋白与左心室肥厚的相关性
Author: Lei ZHU ¹ ; Ming YANG ; Bo CHENG ; Yan XU ; Feng YAO ; Yong ZOU ; Suchuan ZHANG ; Min LIU
Author Information

1. 江汉大学附属医院综合3科武汉430015
Keywords: galactoselectin-3; microalbuminuria; hypertension; left ventricular hypertrophy
From: The Journal of Practical Medicine 2018;34(2):247-250
CountryChina
Language:Chinese
Abstract: Objective To investigate the relationship of galectin 3(Gal-3)and microalbuminuria(MAU) with left ventricular hypertrophy(LVH)in elderly patients with hypertension. Methods 120 patients with LVH were included in the study as LVH group and another patients with non-LVH group as NLVH group with the age, sex ratio and length of stay matched to the LVH group.The conditional Logistic regression was used to analyze the independent risk factors of LVH.Results The single factor analysis showed a positive correlation of LVH with the course of disease,blood pressure control,BMI,NT-proBNP,Gal-3,MAU and education level. By multivariate Logistic regression,course of disease,blood pressure,Gal-3 and MAU were included in the model,with the OR (95% CI)of 1.062(1.001~2.237),1.643(1.527~5.185),2.816(2.231~8.872)and 3.736(3.151~11.391). Conclusion As independent risk factors,the course of disease,control of blood pressure,Gal-3 and MAU are significantly correlated with LVH.