Relationship between the level of human platelet factor IV and Plasmodium falciparum infection

VernacularTitle:人类血小板因子Ⅳ水平与恶性疟原虫感染的关系
Author: Dongde XIE ¹ ; Jiangtao CHEN ; Eyi Monsuy URBANO ; Matesa Apicante ROCIO ; Maximo Miko Ondo Obono ; Ehapo Sala CARLOS ; Ying LI ; Xueyan LIANG ; Min LIN
Author Information

1. 江门市人民医院检验科
Keywords: malaria; platelet factor 4; equatorial Guinea
From: The Journal of Practical Medicine 2018;34(1):132-134,139
CountryChina
Language:Chinese
Abstract: Objective To investigate the relationship between Plasmodium infection and platelet factor Ⅳ(PF4) and to provide the ideas for the treatment of malaria.Methods The serum PF4 concentration was determined with the Enzyme-linked immunosorbent assay (ELISA) in the malaria group (122 cases of malaria patients)and the control group (399 cases of normal).The average value (mean) and positive rate of PF4 were compared between two groups.Results The PF4 level of malaria group was significantly higher than that in the control group and the difference between two groups was statistical significance (P ＜ 0.05).There was no significant difference in Plasmodium falciparum density between the PF4 high level group and the PF4 normal group in the malaria group.Conclusions The expression of human PF4 level has definite relationship with the plasmodium infection of Equatorial Guinea.