Post-laparoscopic analgesic effect of oxycodone combined with dexmedetomidine for gastric cancer patients
10.3969/j.issn.1006-5725.2017.22.030
- VernacularTitle:羟考酮联合右美托咪啶对腹腔镜胃癌患者术后的镇痛效果
- Author:
Yanyun CHEN
1
;
Ling YU
;
Hongyu TAN
Author Information
1. 恶性肿瘤发病机制及转化研究教育部重点实验室
- Keywords:
oxycodone;
dexmedetomidine;
analgesia;
laparoscopic surgery
- From:
The Journal of Practical Medicine
2017;33(22):3795-3798
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the post-laparoscopic analgesic effect of oxycodone combined with dexmedetomidine for gastric cancer patients.Methods A total of 40 gastric cancer patients who underwent laparoscopy during November 2016 and January 2017 and assessed with physical status Ⅰ or Ⅱ according to American Society of Anesthesiologists,were randomly divided into 2 groups:oxycodone group (group O,n =20) and oxycodone plus dexmedetomidine group (group OD,n =20).The anestheasic effects at the time points of hours 2,5,8,11 and 24 after the operation were assessed by using visual analog pain score,times for pressing the pump,Ramsay score and patient's satisfaction index of the two groups.At the same time,the adverse effects of two groups were recorded and observed.Results The analgesic effect after starting the pump at hours 2,5,8,11,24 and 25,the VAS scores and the pressure time in group OD were significantly lower than in group O (P ＜ 0.05),and the Ramsay scores were insignificantly different between the groups (P ＞ 0.05).In group OD,the patient's satisfaction level was significantly higher than in group O (P ＜ 0.05).Nausea,vomiting and dizziness occurred in both groups without significantly difference between the two groups.Conclusion Oxycodone combined with dexmedetomidine can provide satisfactory analgesia for gastric cancer patients receiving laparoscopic surgery.
