Value of αL-fucosidase and its correlation with total bile acids in pregnant women with gestational diabetes mellitus
10.3969/j.issn.1006-5725.2017.22.027
- VernacularTitle:妊娠糖尿病孕妇α-L-岩藻糖苷酶检测价值及其与总胆汁酸的相关性
- Author:
Meixiang GUO
1
;
Fanrong YU
;
Jun LU
;
Linyan WANG
;
Hongtao WANG
;
Xuemei YU
Author Information
1. 201400,上海交通大学附属第六人民医院南院内分泌科
- Keywords:
gestational diabetes mellitus;
α-L-Fucosidase;
total bile acid;
bilirubin;
alkaline phosphatase
- From:
The Journal of Practical Medicine
2017;33(22):3784-3787
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the detection value of α-L-fucosidase (AFU) in gestational diabetes mellitus (GDM) and the correlation of AFU with total bile acids (TBA).Methods Anthropometric parameters and serum biochemical indexes were recorded and 75 g OGTT was performed then according to OGTT result,patients with GDM were confirmed and matched the control group by age and BMI.Results The level of AFU in GDM group was higher than that that of normal glucose tolerance (NGT) group and associated with 1 hour postprandial glucose.After correcting ALT and HbA1c,AFU correlated with TBA.Conclusions During pregnancy,AFU has reference value for the diagnosis of GDM and 1 hour postprandial glucose is its independent factor.The rise AFU is combined with the decrease of.DBIL but the increase of TBA and ALP,which indicates bile duct system in patients with GDM is in an active state.
