Clinical study of parenteral nutrition with ω-3 fatty acids in critically ill cancer patients
10.3969/j.issn.1006-5725.2017.22.017
- VernacularTitle:ω-3脂肪酸肠外营养治疗重症肿瘤患者的临床研究
- Author:
Xianlong XIE
1
;
Cheng WANG
;
Yang LI
;
Yingming HUANG
;
Qifang LAO
;
Yili HE
;
Kunpeng BU
Author Information
1. 广西医科大学附属肿瘤医院重症医学科
- Keywords:
ω-3 fatty acids;
parenteral nutrition;
critically ill;
cancer patients
- From:
The Journal of Practical Medicine
2017;33(22):3745-3748
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of parenteral nutrition with ω-3 fatty acids on nutrition,inflammatory response,immunity and prognosis in criticallyill cancer patients.Methods 60 critically ill cancer patients were randomly divided into study group and the control group,30 cases each.All Patients were given isonitrogen and isocalorie enteral and parenteral nutrition for 2 weeks,which added ω-3 fatty acids in the study group by parenteral nutrition.The indicators of nutrition,inflammation,immune function were detected weekly.prognostic indicators (mortality,intensive care unit [ICU] length of stay,infectious complications) were compared.Results The indicators of nutrition,inflammatory reaction and immune function of study group were significantly improved than control group,and length of stay in ICU of study group was shorter than control group.There were less mortality and morbidity of infection complications in the study group compared with control group,but difference were not significant (P =0.13 and P=0.165).Conclusion ω-3 fatty acids supplementation of parenteral nutrition in critically ill cancer patients can improve nutritional status and immune function,reduce inflammatory response,shorten ICU length of stay,but not significantly improve ICU mortality and reduce infectious complications.
