Clinical evaluation of the anti-gingivitis efficacy of a novel stabilized stannous-containing sodium fluoride dentifrice
10.3969/j.issn.1001-3733.2018.02.024
- VernacularTitle:一种新型含稳定亚锡-氟化钠牙膏治疗牙龈炎患者的临床效果评价
- Author:
Xin ZHANG
1
;
Tao HE
;
Jiahui LI
;
Yanyan HE
;
Ning JI
;
Lili SUN
;
Xin LI
;
Jinlan CHANG
;
Ying CHANG
;
Jizhi ZHAO
Author Information
1. 中国医学科学院北京协和医院口腔科
- Keywords:
Dentifrice;
Stannous;
Gingivitis;
Gingival bleeding;
Pocket depth;
Randomized clinical trial
- From:
Journal of Practical Stomatology
2018;34(2):257-259
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To evaluate the anti-gingivitis efficacy of a novel stabilized stannous-containing sodium fluoride dentifrice. Methods: A randomized, controlled and double blind clinical study was conducted. 156 adults with gingivitis were enrolled and randomly assigned to experimental group(group of novel stabilized stannous-containing sodium fluoride dentifrice, n = 51), positive control group (group of Yunnan Baiyao dentifrice, n = 54) and negative control group (group of Crest dentifrice, n = 51). Gingival health was assessed using Mazza Modification of the Papillary Bleeding Index(Mazza GI) at Baseline, day 3 and week 4 and pocket depth was evaluated at baseline and week 4, respectively. Results: At day 3 and week 4, the experimental and positive control groups exhibited lower clinical parameters than the negative control group(P＜ 0. 000 1). At week 4, the mean Mazza GI scores and PD of the experimental group were significantly lower than those of the positive control group(P＜ 0. 05). Conclusion: The novel stannous-containing sodium fluoride dentifrice has anti-gingivitis efficacy.
